ASSESSMENT OF SERUM LEPTIN, LIPID PROFILE, GLUCOSE LEVEL, INSULIN RESISTANCE AND BMI IN PATIENTS WITH SKIN TAGS

Erdinc Terzi, Fatma Ceyla Eraldemir, Irem Yavas

Abstract


Background: Skin tags are small, soft, pedunculated papillomas, usually occurring on the neck, axillae and eyelids. Skin tags are associated with obesity and atherogenic profile.

Aim: The aim of this study was to evaluate the relationship between serum leptin, body mass index, lipid profile, fasting glucose, insulin levels and homeostasis model assessment of insulin resistance in patients with skin tags and to compare them with the levels in healthy controls.

Materials and Methods: This study included 84 participants, 45 skin tags patients and 39 apparently healthy controls. Body mass index, fasting glucose and insulin levels were estimated in addition to lipid profile, leptin and homeostasis model assessment of insulin resistance levels.

Results: The skin tags group showed significantly higher values of age,
total cholesterol, low-density lipoprotein cholesterol, body mass index, triglicerides, very low-density lipoprotein cholesterol and homeostasis model assessment of insulin resistance, when compared with the healthy control group. There was no significant difference in sex, leptin levels, high-density lipoprotein cholesterol, glucose and insulin levels between the two groups.

Conclusion: The results of this study confirm that skin tags are associated with obesity and dyslipidemia. Therefore, follow-up of these patients regarding to development of atherosclerosis associated diseases may be beneficial.


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—Print : ISSN 2392–7461, ISSN-L 2392–7461 
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